Good day Mark.

There are no distros that I know of, perhaps you can create your own.
Some projects that are out there:

[Slax] - is based on Slackware GNU Linux. There are also available all scripts and source codes, which can be used to build your own live CD.

or you can use Gentoo.

Hope this helps.

God bless.

Mark wrote:

Does anyone know of a knoppix-like distro that has SE Linux support?

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Jayendren Anand Maduray
Senior IT Administrator
Perinatal HIV Research Unit
University of Witwaterstrand